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Anteroseptal and Midseptal Accessory Pathways

Raja Selvaraj
Professor of Cardiology
JIPMER

Anatomy and terminology

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Triangle of Koch

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Risk of AV block

Where do you get AV block on the septum

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Pediatric registry

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Schaffer MS, Silka MJ, Ross BA, Kugler JD. Inadvertent atrioventricular block during radiofrequency catheter ablation. Results of the Pediatric Radiofrequency Ablation Registry. Pediatric Electrophysiology Society. Circulation. 1996 Dec 15;94(12):3214-20.

Ablation over HB and risk of AV block

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Xue Y, … Kuck KH, Yen Ho S, Ouyang F. Experimental, Pathologic, and Clinical Findings of Radiofrequency Catheter Ablation of Para-Hisian Region From the Right Ventricle in Dogs and Humans. Circ Arrhythm Electrophysiol. 2017 Jun;10(6):e005207. doi: 10.1161/CIRCEP.116.00520728630174.

So how do you avoid AV block ?

  • Awareness of risk
  • Ability to monitor AV conduction during ablation
  • Assess for His bundle capture

Mapping approaches

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Mapping retrograde

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Mapping antegrade

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Target

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Slant and isolated potential

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Otomo K …Jackman WM. Reversing the direction of paced ventricular and atrial wavefronts reveals an oblique course in accessory AV pathways and improves localization for catheter ablation. Circulation. 2001 Jul 31;104(5):550-6. doi: 10.1161/hc3001.093499.

Anteroseptal pathways

Stability

  • Long sheath
  • IJV approach

Curve

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Ablation during ORT

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Mapping echo beats

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Ablation from NCC

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Optimal signal

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Suleiman M, Brady PA, Asirvatham SJ, Friedman PA, Munger TM. The noncoronary cusp as a site for successful ablation of accessory pathways: electrogram characteristics in three cases. J Cardiovasc Electrophysiol. 2011 Feb;22(2):203-9. doi: 10.1111/j.1540-8167.2010.01811.x.

Midseptal pathways

ECG

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Cryoablation

  • Reversible cryomapping makes it safer
  • Consider when risk of AV block high
  • Especially in children

Cryoablation vs RF ablation

  • Acute success similar (93% vs. 87%)
  • No AV block
  • Less recurrence (14% vs. 30%)
  • Less mechanical trauma (6% vs. 20%)

Dos Santos Sousa IB, Chokr MO, Melo SL, Pisani CF, Hardy CA, de Moura LG, Sacilotto L, Wu TC, Darrieux FCC, Scanavacca MI. Comparison between cryotherapy and radiofrequency energy sources for parahisian accessory pathway percutaneous ablation. J Interv Card Electrophysiol. 2024 Dec;67(9):1981-1991. doi: 10.1007/s10840-024-01841-8. Epub 2024 Jun 4. PMID: 38833098.

Summary

  • Subset of accessory pathways characterised by high risk of AV block
  • Understanding of anatomy and risk of AV block at different areas
  • Ablate in a manner that AV block can be identified
  • Cryoablation may be preferred in children and in midseptal pathways